Ultra-high-field 7T MRI reveals changes in human medial temporal lobe volume in female adults during menstrual cycle | Nature Mental Health
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Main Ovarian hormones are powerful modulators of neuroplasticity, with animal research offering robust evidence of endocrine regulation of brain morphology on a rapid timescale1. In the timescale of hours to days, rodent and non-human primate studies have demonstrated that estradiol and progesterone elicit modulatory effects on cell proliferation1, dendritic spine and synapse density2,3,4,5, mitochondrial and synaptic health6,7, synaptic sprouting and axon growth8,9,10, and myelination11, suggesting a pivotal role of ovarian hormones in brain structural organization. In humans, the…
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