Precise coupling of the thalamic head-direction system to hippocampal ripples | Nature Communications
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Advertisement Nature Communications volume 11, Article number: 2524 (2020) Cite this article 7783 Accesses 28 Citations 54 Altmetric Metrics details The anterior thalamus is a key relay of neuronal signals within the limbic system. During sleep, the occurrence of hippocampal sharp wave-ripples (SWRs), believed to mediate consolidation of explicit memories, is modulated by thalamocortical network activity, yet how information is routed around SWRs and how this communication depends on neuronal dynamics remains unclear. Here, by simultaneously recording ensembles of neurons in the anterior thalamus and local field potentia
Introduction Thalamocortical loops form the canonical circuits of the most complex cognitive functions1,2,3,4. The dorsal thalamus (henceforth referred to as the thalamus for simplicity) is organized in a large family of cytoarchitectonically defined nuclei1. Among them, the anterior thalamic nuclei (AT) are located at the central stage of the Papez circuit5 and play a key role in memory6,7, spatial navigation8,9,10, and arousal states11,12. However, the dynamics of AT neurons and their functional integration with the limbic system remain elusive. The role of AT in navigation is indicated…
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