Arousal as a universal embedding for spatiotemporal brain dynamics | Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
Main The past decade has seen a proliferation of research into the organizing principles, physiology and function of ongoing brain activity and brain ‘states’ as observed across various recording modalities, spatiotemporal scales and species12,13,14. Ultimately, it is of interest to understand how such wide-ranging phenomena are coordinated within a functioning brain. However, as different domains of neuroscience have evolved around unique subsets of observables, the integration of this research into a unified framework remains an outstanding challenge15. Interpreting ongoing neural…
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