Arousal as a universal embedding for spatiotemporal brain dynamics | Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
Main The past decade has seen a proliferation of research into the organizing principles, physiology and function of ongoing brain activity and brain ‘states’ as observed across various recording modalities, spatiotemporal scales and species12,13,14. Ultimately, it is of interest to understand how such wide-ranging phenomena are coordinated within a functioning brain. However, as different domains of neuroscience have evolved around unique subsets of observables, the integration of this research into a unified framework remains an outstanding challenge15. Interpreting ongoing neural…
saved by
related reading
- Mechanistic Interpretability: A Challenge Common to Both Artificial and Biological Intelligencekempnerinstitute.harvard.edu
- Computational and systems neuroscience: The next 20 yearspmc.ncbi.nlm.nih.gov
- A brain-wide map of neural activity during complex behaviournature.com
- https://io0.github.ioio0.github.io
- Breathing coordinates cortico-hippocampal dynamics in mice during offline statesnature.com
- The missing half of the neurodynamical systems theorythetransmitter.org
- Dimensionality reduction in neural data analysisxcorr.net
- POYO-1poyo-brain.github.io
- 2205.08413.pdfarxiv.org
- Towards a “universal translator” for neural dynamics at single-cell, single-spike resolutionarxiv.org
- Notes towards Neurostimulation and Mathematical Neurosciencebernoullicollective.org
- Neural manifolds: Latest buzzword or pathway to understand the brain?thetransmitter.org