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A brain-wide map of neural activity during complex behaviour | Nature

nature.com · 8,983 words · saved by 2 readers

The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task in mice.

Main It is unclear how hundreds of interconnected brain areas that are processing information related to sensation, decisions, action and behaviour lead to coherent and effective outputs2,3,4. To answer this question, we need to know how the activities of individual neurons and populations of neurons across the brain reflect variables such as stimuli, expectations, choices, actions, rewards and punishments5. Electrophysiological recordings from animals have been instrumental in this exploration. Until recently, however, technical limitations have restricted these recordings to a limited…

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