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Making the invisible visible – laser phase plate cryo-EM

biohub.org · 2,702 words · saved by 1 readers

Biohub built a laser phase plate into a cryo-EM microscope — now proteins once too small to see are coming into focus inside intact cells.

Making the invisible visible – laser phase plate cryo-EM Skip to content ← Back to News June 11, 2026 Making the invisible visible A landmark achievement in microscopy is poised to reveal the molecular machinery of life inside cells, at near-atomic detail. Imaging A visualization of the dual-laser phase plate — a collaboration between UC Berkeley and Biohub. Two precision mirrors bounce laser light back and forth, building to an intensity 100 million times brighter than the Sun’s surface, enabling scientists to see the detailed inner workings of cells with more clarity and contrast than ever b

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