子昂 楊
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- Acquired Hemophilia - Symptoms, Causes, Treatment | NORD1 savers
- Approach to the adult with lymphocytosis or lymphocytopenia - UpToDate1 savers
- Marginal Zone Lymphoma - DynaMed1 savers
- Chronic lymphocytic leukemia - AMBOSS1 savers
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highlights · 640
In individuals with a factor deficiency the normal plasma restores the test value to normal; in individuals with a factor inhibitor it does not.
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDmixing patient’s plasma with normal plasma
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDPT is sensitive to coagulation proteins synthesized by the liver (FII, FVII, FIX,
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDaPTT is sensitive mainly to FVIII, FIX, FXI and XII
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDan isolated prolongation of the activated partial thromboplastin time (aPTT)
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDVon Willebrand disease
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDThe majority of cases involve deficiency of factor VIII (acquired hemophilia A). A handful of cases have been described that involve deficiency of factor IX (acquired hemophilia B).
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDSubcutaneous bleeding (ecchymoses) is the most common manifestation of AH followed by muscle bleeding (hematoma), gastrointestinal (melena), genitourinary (hematuria) and retroperitoneal.
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDcongenital hemophilia, a group of rare genetic disorders caused by mutations in the genes encoding certain clotting factors
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDabnormal, uncontrolled bleeding into the muscles, skin and soft tissue that can occur spontaneously
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDIn AH, the body produces antibodies (known as inhibitors) that attack clotting factors, most often factor VIII
Acquired Hemophilia - Symptoms, Causes, Treatment | NORDHemolytic anemia or pure red cell aplasia associated with CLL
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateThat is, the likelihood of a malignant disorder increases with ALC >30,000/microL
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateALCs can rise to 20,000 to 30,000 cells/microL in reactive lymphocytoses (eg, infection or inflammation)
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateAcute lymphoblastic leukemia (ALL) may be derived from T, B, or NK cells, and can present at any age.
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateCLL is defined by the presence of ≥5000 lymphocytes/microL
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateMost patients with MBL have an immunophenotype that is indistinguishable from CLL
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateB lymphocytes <5000 cells/microL in peripheral blood (ie, below the threshold for diagnosis of chronic lymphocytic leukemia [CLL]),
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateMonoclonal B lymphocytosis — Monoclonal B cell lymphocytosis
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDatecytomegalovirus (CMV
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateEpstein-Barr virus (EBV)
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDatemalignant process or in response to an infectious or inflammatory stimulus
Approach to the adult with lymphocytosis or lymphocytopenia - UpToDateCD23 negative or positive (nodal marginal zone lymphoma may be positive in only 8% of cases)
Marginal Zone Lymphoma - DynaMedCD20 positive CD10 negative CD5 negative (
Marginal Zone Lymphoma - DynaMedtypical immunophenotype for both splenic and nodal marginal zone lymphoma
Marginal Zone Lymphoma - DynaMedtypical immunophenotype on flow cytometry of peripheral blood or bone marrow trephine biopsy
Marginal Zone Lymphoma - DynaMedmorphology on peripheral blood, and on bone marrow biopsy showing characteristic intrasinusoidal lymphocytic infiltration
Marginal Zone Lymphoma - DynaMedspleen, lymph nodes, and mucosa-associated lymphoid tissues (MALT)
Marginal Zone Lymphoma - DynaMedDiagnosis requires persistent monoclonal lymphocytosis plus CLL immunophenotype confirmed by flow cytometry.
Chronic lymphocytic leukemia - AMBOSSprognostic markers del(17p) and TP53 mutation
Chronic lymphocytic leukemia - AMBOSSa type of B-cell malignancy that manifests with lymphocytic leukocytosis
Chronic lymphocytic leukemia - AMBOSSimmunophenotypic markers consistent with CLL on flow cytometry
Chronic lymphocytic leukemia - AMBOSSsmall mature lymphocytes and smudge cells
Chronic lymphocytic leukemia - AMBOSSAnterior approaches are superior to posterior techniques for > 60% OPLL canal occupancy with cervical kyphosis. Surgeons should be prepared for dural ossification and/or adherence if removal of OPLL is performed
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkCSF leakage, implant complications, dysphagia, dysphonia were more common in anterior
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkC5 palsy and neck pain were more common in posterior
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinka 21.8% complication rate with similar rates between anterior and posterior procedure
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkthree basic types of dural ossification: “isolated” type found at a distance from OPLL, “double layer” found posterior to OPLL lesions, and “en bloc” found in continuity with the OPLL lesion
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkK-line positive lateral X-ray (i.e., the OPLL does not extend dorsal to the K-line) are associated with improved outcomes after posterior-based decompressions
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkkyphosis line or “K-line” is a straight line connecting midcanal C2 to C7 used as a radiographic predictor of successful posterior based decompression.
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkchanges in balance or gait stability, loss of fine manual motor control or dexterity, nonspecific upper and lower extremity weakness, paresthesias, and pain.
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkaxial neck pain, radiculopathy, and myelopathy.
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkhypophosphatemic rickets
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkboth genetic and environmental factors
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkbetween 1.9 and 4.3%, and in other Asian countries
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkOPLL is more frequently seen in older adults (40–60 years old) and in males
Ossification of the posterior longitudinal ligament in the cervical spine: a review | SpringerLinkWe do not test nonspecific panels of hormone levels or nonhormonal tumor biomarkers such as CgA for patients with nonfunctioning tumors,
Classification, epidemiology, clinical presentation, localization, and staging of pancreatic neuroendocrine neoplasms - UpToDateSpecific hormones secreted by functional tumors (ie, insulin, proinsulin, glucagon, gastrin, vasoactive intestinal polypeptide)
Classification, epidemiology, clinical presentation, localization, and staging of pancreatic neuroendocrine neoplasms - UpToDatepancreatic polypeptide (PP)
Classification, epidemiology, clinical presentation, localization, and staging of pancreatic neuroendocrine neoplasms - UpToDatechromogranin A (CgA)
Classification, epidemiology, clinical presentation, localization, and staging of pancreatic neuroendocrine neoplasms - UpToDate