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Clinical manifestations and treatment of Epstein-Barr virus infection - UpToDate

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Clinical manifestations and treatment of Epstein-Barr virus infection INTRODUCTION Epstein-Barr virus (EBV) is a widely disseminated herpesvirus that is spread by intimate contact between susceptible persons and asymptomatic EBV shedders. EBV is the primary agent of infectious mononucleosis (IM), persists asymptomatically for life in nearly all adults, and is associated with the development of B cell lymphomas, T cell lymphomas, Hodgkin lymphoma, nasopharyngeal carcinoma, and gastric carcinomas in certain patients [1]. Reactivation disease is not a prominent issue with EBV, in contrast to…

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