Research – Zeno Research Group
Cellular membranes provide critical interfaces for the biochemical interactions that regulate cell behavior and function. These membranes are composed of a heterogeneous mixture of lipids and proteins. Understanding and controlling biomolecular interactions that occur at membranes is challenging owing to the inherent ability of the membrane environment to functionally couple interactions between proteins and lipids. Nonetheless, elucidating the interplay between proteins and lipids in biological membranes is important for a variety of applications, such as pinpointing the mechanisms of disease, discovering and delivering new drugs, and developing functional biomaterials. Toward addressing these challenges, our group uses engineering principles and fluorescence techniques to develop the tools, approaches, and ideas that will enable us to understand and control the protein-lipid interface. Lipid bilayers are the primary structural component of cellular membranes and are resistant to defo
Overview Cellular membranes provide critical interfaces for the biochemical interactions that regulate cell behavior and function. These membranes are composed of a heterogeneous mixture of lipids and proteins. Understanding and controlling biomolecular interactions that occur at membranes is challenging owing to the inherent ability of the membrane environment to functionally couple interactions between proteins and lipids. Nonetheless, elucidating the interplay between proteins and lipids in biological membranes is important for a variety of applications, such as pinpointing the mechanisms o
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