Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing - PMC

The ability of proteins to sense membrane curvature is essential to cellular function. All known sensing mechanisms rely on protein domains with specific structural features such as wedge-like amphipathic helices and crescent-shaped BAR domains. ...

Nat Commun . 2018 Oct 8;9:4152. doi: 10.1038/s41467-018-06532-3 Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing Wade F Zeno Wade F Zeno 1 Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712 USA Find articles by Wade F Zeno 1 , Upayan Baul Upayan Baul 2 Department of Chemistry, The University of Texas at Austin, Austin, TX 78712 USA Find articles by Upayan Baul 2 , Wilton T Snead Wilton T Snead 1 Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712 USA Find ar

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