Quantifying the effect of experimental perturbations at single-cell resolution | Nature Biotechnology

Matched treatment and control single-cell RNA sequencing samples are more accurately compared at the single-cell level.

References Luecken, M. D. & Theis, F. J. Current best practices in single-cell RNA-seq analysis: a tutorial. Mol. Syst. Biol. 15, e8746 (2019). Article PubMed PubMed Central Google Scholar Weinreb, C., Wolock, S., Klein, A. M. & Berger, B. SPRING: a kinetic interface for visualizing high dimensional single-cell expression data. Bioinformatics 34, 1246–1248 (2018). Article CAS PubMed Google Scholar Moon, K. R. et al. Visualizing structure and transitions in high-dimensional biological data. Nat. Biotechnol. 37, 1482–1492 (2019). Article CAS PubMed PubMed Central Google Scholar van…

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