Memory formation in the absence of experience | Nature Neuroscience
Pairing an odor conditioned stimulus (CS) with an unconditioned stimulus (US) induces memory formation. Vetere et al. replace the real CS and US with direct optogenetic stimulation of the brain and create a fully artificial odor memory in mice.
Data availability All data supporting the findings of this study are available from the corresponding author upon request. Code availability Custom code for behavioral analysis is available from the corresponding author upon request. References Eichenbaum, H. Still searching for the engram. Learn. Behav. 44, 209–222 (2016). Article Google Scholar Josselyn, S. A., Kohler, S. & Frankland, P. W. Finding the engram. Nat. Rev. Neurosci. 16, 521–534 (2015). Article CAS Google Scholar Tonegawa, S., Liu, X., Ramirez, S. & Redondo, R. Memory engram cells have come of age. Neuron 87,…
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