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Optogenetics - Wikipedia

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Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways.[1] In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making,[2] learning,[3] fear memory,[4] mating,[5] addiction,[6] feeding,[7] and locomotion.[8] In a first medical application of optogenetic technology, vision was partially restored in a blind patient with Retinitis pigmentosa.[9] Optogenetic techniques have also been introduced to map the functional connectivity of the brain.[10][11] By altering the activity of genetically labelled neurons with light and by using imaging and electrophysiology techniques to record the

Optogenetics - Wikipedia Jump to content From Wikipedia, the free encyclopedia Controlling biological cells with light This article is about controlling cellular activity with light. For genetically encoded sensors, see Optogenetic methods to record cellular activity . Optogenetics is a biological technique used to characterize and manipulate the activity of neurons or other cell types with light . This is achieved by expression of light-sensitive ion channels, pumps or enzymes in the target brain cells. A specialization of this field is nano-optogenetics . [ 1 ] On the level of indivi

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