Epidemiology and risk factors for esophageal cancer - UpToDate
The majority of esophageal cancers (EC) are squamous cell or adenocarcinomas. Although the incidence of squamous cell carcinoma (SСС) is decreasing in the United States, the incidence of adenocarcinoma (AC) arising out of Barrett's esophagus (ΒE) is rising dramatically, although less so in the last few years [1]. When stratified according to anatomic location, most of the increased incidence involves tumors at the esophagogastric junction (EGJ) and gastric cardia (figure 1)[2]. The epidemiology, etiologic factors, and pathobiology of AC and SСС of the esophagus will bе reviewed here. Small cell carcinoma, sarcomas, and other rare tumors that arise in the esophagus and EGJ, as well as the clinical manifestations, diagnosis, and staging of EC, are discussed separately. (See "Extrapulmonary small cell cancer" and "Local treatment for gastrointestinal stromal tumors, leiomyomas, and leiomyosarcomas of the gastrointestinal tract", section on 'Esophagus' and "Clinical manifestations, diagnos
Epidemiology and risk factors for esophageal cancer INTRODUCTION The majority of esophageal cancers (EC) are squamous cell or adenocarcinomas. Although the incidence of squamous cell carcinoma (SCC) is decreasing in the United States, the incidence of adenocarcinoma arising out of Barrett's esophagus (BE) is rising dramatically, although less so in the last few years [1-4]. When stratified according to anatomic location, most of the increased incidence involves tumors at the gastroesophageal junction (GEJ), which can also be called the esophagogastric junction (EGJ), and gastric cardia…
saved by
related reading
- Clinical presentation, diagnosis, and staging of esophageal canceruptodate.com
- Barrett's esophagus: Epidemiology, clinical manifestations, and diagnosisuptodate.com
- Barrett's esophagus: Epidemiology, clinical manifestations, and diagnosisuptodate.com
- Current Status of Mucosal Imaging with Narrow-Band Imaging in the Esophagusncbi.nlm.nih.gov
- Gastric cancer: Pathology and molecular pathogenesisuptodate.com
- Early gastric cancer: Clinical features, diagnosis, and staginguptodate.com
- Early gastric cancer: Clinical features, diagnosis, and staginguptodate.com
- Multiband mucosectomy for advanced dysplastic lesions in the upper digestive tractncbi.nlm.nih.gov
- Safety and efficacy of multiband mucosectomy for Barrett’s esophagus: a systematic review with pooled analysis - PMCncbi.nlm.nih.gov
- Risk factors for gastric canceruptodate.com
- Pathophysiology of gastroesophageal reflux diseaseuptodate.com
- How to Interpret Esophageal Impedance pH Monitoring - PMCpmc.ncbi.nlm.nih.gov