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Risk factors for gastric cancer INTRODUCTION Gastric cancer has significant geographic, ethnic, and socioeconomic differences in distribution. This topic review will discuss risk factors for gastric cancer. Epidemiologic aspects are presented separately. (See "Epidemiology of gastric cancer".) There are two main histologic variants of gastric adenocarcinoma. The most frequent is the "intestinal type," so called because of its morphologic similarity to adenocarcinomas arising in the intestinal tract. The less common "diffuse type" gastric cancers are characterized by a lack of…
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