Psoralen plus ultraviolet A (PUVA) photochemotherapy - UpToDate
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Psoralen plus ultraviolet A (PUVA) photochemotherapy INTRODUCTION Psoralen plus ultraviolet A (PUVA) photochemotherapy combines the administration of psoralens, a class of phototoxic plant-derived compounds, with exposure to ultraviolet A (UVA) radiation. PUVA is used for the treatment of a variety of skin diseases, including psoriasis, mycosis fungoides, eczema, vitiligo, and graft-versus-host disease [1-3]. This topic will discuss the mechanism of action, treatment protocols, contraindications, adverse effects, and clinical indications of PUVA therapy. The use of PUVA for the treatment…
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