Clinical manifestations, pathologic features, and diagnosis of acute promyelocytic leukemia in adults - UpToDate
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Clinical manifestations, pathologic features, and diagnosis of acute promyelocytic leukemia in adults INTRODUCTION Acute myeloid leukemia (AML) refers to a group of hematopoietic neoplasms involving cells committed to the myeloid lineage. Acute promyelocytic leukemia (APL) is a biologically and clinically distinct variant of AML. APL was classified as AML-M3 in the older French-American-British (FAB) classification system and is currently classified as acute promyelocytic leukemia with t(15;17)(q24.1;q21.2);PML::RARA [1,2]. (See "Acute myeloid leukemia: Classification".) APL represents a…
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