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Overview of the treatment of acute lymphoblastic leukemia/lymphoma in children and adolescents - UpToDate

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Treatment of acute lymphoblastic leukemia/lymphoma in children and adolescents INTRODUCTION Acute lymphoblastic leukemia/lymphoma (ALL/LBL) is the most common cancer in children, accounting for nearly one-third of all childhood malignancies. ALL and LBL are considered the same disease, distinguished only by the primary location of the disease and level of bone marrow involvement. Overall survival for children with ALL/LBL is >90 percent and has improved dramatically since the 1980s due, in part, to successive research protocols that improved clinical outcomes while reducing toxicity.…

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