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McGovern neuroscientists develop a new model for autism - MIT McGovern Institute

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By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders. Shank3 is a protein that in humans is encoded by the SHANK3 gene on chromosome 22. Image: Wikipedia Anne Trafton | June 12, 2019 Categories: Systems Neuroscience, Cellular & Molecular Neuroscience, Genome Engineering, Autism Spectrum Disorder, Robert Desimone, Guoping Feng, Poitras Center for Psychiatric Disorders Research, Hock E. Tan and K. Lisa Yang Center for Autism Research By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders. Using the genome-editing system CRISPR, researchers at MIT and in China have engineered macaque monkeys to express a gene mutation linked to autism and other neurodevelopmental disorders in humans. These monkeys show some behavioral traits and brain connectivity patterns similar to those seen in humans wit

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders. Shank3 is a protein that in humans is encoded by the SHANK3 gene on chromosome 22. Image: Wikipedia By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders. Shank3 is a protein that in humans is encoded by the SHANK3 gene on chromosome 22. Image: Wikipedia Using the genome-editing system CRISPR , researchers at MIT and in China have engineered macaque

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