Diagnosis and differential diagnosis of rheumatoid arthritis - UpToDate
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INTRODUCTION — Rheumatoid arthritis (RA) is a symmetric, inflammatory, peripheral polyarthritis of unknown etiology. Active RA destroys joints through the erosion of cartilage and bone. Untreated, it leads to loss of physical function, inability to carry out daily tasks of living, and difficulties in maintaining employment. Uncontrolled inflammation have other health risks, including higher rates of cardiovascular disease, osteoporosis, and certain types of cancer (eg, lymphoma). Early recognition and treatment with disease-modifying antirheumatic drugs (DMARDs) are important to prevent…
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