CG-dinucleotide suppression enables antiviral defense targeting non-self RNA - PMC

Vertebrate genomes exhibit marked CG-suppression, that is lower than expected numbers of 5′-CG-3′ dinucleotides[] . This feature is likely due to C-to-T mutations that have accumulated over hundreds of millions of years, driven by CG-specific ...

Nature . Author manuscript; available in PMC: 2019 Jun 25. Published in final edited form as: Nature. 2017 Sep 27;550(7674):124–127. doi: 10.1038/nature24039 CG-dinucleotide suppression enables antiviral defense targeting non-self RNA Matthew A Takata Matthew A Takata 1 Laboratory of Retrovirology, The Rockefeller University, New York, NY Find articles by Matthew A Takata 1 , Daniel Gonçalves-Carneiro Daniel Gonçalves-Carneiro 1 Laboratory of Retrovirology, The Rockefeller University, New York, NY Find articles by Daniel Gonçalves-Carneiro 1 , Trinity Zang Trinity Zang 1 Laboratory of Retrovir

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