Keeping Uracil Out of DNA: Physiological Role, Structure and Catalytic Mechanism of dUTPases - PMC
The thymine-uracil exchange constitutes one of the major chemical differences between DNA and RNA. Although these two bases form the same Watson-Crick base pairs with adenine and are equivalent for both information storage and transmission, uracil incorporation ...
. Author manuscript; available in PMC: 2009 Aug 27. Published in final edited form as: Acc Chem Res. 2009 Jan 20;42(1):97–106. doi: 10.1021/ar800114w CONSPECTUS The thymine-uracil exchange constitutes one of the major chemical differences between DNA and RNA. Although these two bases form the same Watson-Crick base pairs with adenine and are equivalent for both information storage and transmission, uracil incorporation in DNA is usually a mistake that needs to be excised. There are two ways for uracil to appear in DNA: thymine replacement and cytosine deamination. Most DNA polymerases…
saved by
related reading
- RNA editing enzymes: structure, biological functions and applicationscellandbioscience.biomedcentral.com
- Cell Biology: DNA Structure & Base Pairingditki.com
- CG-dinucleotide suppression enables antiviral defense targeting non-self RNA - PMCncbi.nlm.nih.gov
- Nucleoside triphosphate - Wikipediaen.wikipedia.org
- Transcription (biology)en.wikipedia.org
- DNA - Wikipediaen.wikipedia.org
- Polyadenylation and nuclear export of mRNAs - PMCncbi.nlm.nih.gov
- Nucleotide base - Wikipediaen.wikipedia.org
- Riboswitches, RNA Regulation | Learn Science at Scitablenature.com
- Hoogsteen base pair - Wikipediaen.wikipedia.org
- DNA Topologyyoutube.com
- Codon usage bias - Wikipediaen.wikipedia.org