Competition | Open Problems in Single Cell Analysis

Open Problems NeurIPS Competition 2021

Summary Scaling from a dozen cells a decade ago to millions of cells today, single-cell measurement technologies are driving a revolution in the life sciences. Recent advances make it possible to measure multiple high-dimensional modalities (e.g. DNA accessibility, RNA, and proteins) simultaneously in the same cell. Such data provides, for the first time, a direct and comprehensive view into the layers of gene regulation that drive biological diversity and disease. In 2021 , we organized the first single-cell analysis competition at NeurIPS bringing together 280 participants to compete on an a

related reading

• Virtual Cell Challengevirtualcellchallenge.org
• ML Contestsmlcontests.com
• Evaluating the role of pretraining dataset size and diversity on single-cell foundation model performancenature.com
• Quantifying the effect of experimental perturbations at single-cell resolutionnature.com
• Kaggle Solutionsfarid.one
• Arc Institute’s first virtual cell model: <span style="font-variant: small-caps">S<span style="font-weight: bolder">tate</span></span> | Arc Institutearcinstitute.org
• [2203.07814] Competition-Level Code Generation with AlphaCodearxiv.org
• Towards building a World Model to simulate perturbation-induced cellular dynamics by AlphaCellbiorxiv.org
• scGen predicts single-cell perturbation responsesnature.com
• Virtual Cell Challenge 2025 Wrap-Up: Winners and Reflections | Arc Institutearcinstitute.org
• Virtual Cell Challengevirtualcellchallenge.org
• PREDICTING SINGLE-CELL PERTURBATION RESPONSES FOR UNSEEN DRUGSarxiv.org