Determine exact optimal parameters of 3D-printed holographic acoustic lenses for transcranial FUS
Determine the exact physical parameter values that define the optimal 3D‑printed holographic acoustic lens for correcting transcranial focused ultrasound aberrations using single‑element transducers, specifically quantifying the polymer p‑wave speed and the resulting lens thickness under a given 3D‑printer voxel size and typical transducer–target configurations, beyond the current trend‑based interval of desirable thicknesses evidenced by simulations and experiments.
The paper evaluates how polymer p‑wave speed and resulting lens thickness influence the performance of 3D‑printed holographic acoustic lenses used to correct skull‑induced aberrations in transcranial focused ultrasound. Through simulations and a validation experiment, the authors identify optimal thickness ranges (in voxels) that appear largely independent of frequency, aperture, and distance, but they do not pin down exact optimal parameter values. In the discussion, the authors state that a more comprehensive set of simulations (varying wavelength, transducer–target distances, lens…
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