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Predictive neural computations in the cerebellum contribute to motor planning and faster behavioral responses in larval zebrafish - PMC

pmc.ncbi.nlm.nih.gov · 9,462 words · saved by 1 readers

The ability to predict the future based on past experience lies at the core of the brain’s ability to adapt behavior. However, the neural mechanisms that participate in generating and updating predictions are not clearly understood. Further, the ...

Abstract The ability to predict the future based on past experience lies at the core of the brain’s ability to adapt behavior. However, the neural mechanisms that participate in generating and updating predictions are not clearly understood. Further, the evolutionary antecedents and the prevalence of predictive processing among vertebrates are even less explored. Here, we show evidence of predictive processing via the involvement of cerebellar circuits in larval zebrafish. We presented stereotyped optic flow stimuli to larval zebrafish to evoke swims and discovered that lesioning the…

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