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Visuomotor decision-making through multifeature convergence in the larval zebrafish hindbrain | Nature Communications

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How do animals use sensory streams to guide behavior? Here the authors show that larval zebrafish process motion and luminance via three feature-specific parallel visual pathways, which are combined to flexibly control sensorimotor decision-making.

Introduction Animals continuously process noisy and often conflicting sensory information from their complex, dynamic environment to guide movement decisions. The precise neural mechanisms that allow the brain to extract and computationally process such cues remain poorly understood. Multiple sensory streams can be combined through, for example, additive or winner-takes-all algorithms. For instance, when an animal attends to different targets, directing its gaze toward the averaged location can provide an effective solution1,2. Such an additive strategy has been observed across various…

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