From Maxwell's equations to the theory of current‐source density analysis - PMC

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Abstract Despite the widespread use of current‐source density (CSD) analysis of extracellular potential recordings in the brain, the physical mechanisms responsible for the generation of the signal are still debated. While the extracellular potential is thought to be exclusively generated by the transmembrane currents, recent studies suggest that extracellular diffusive, advective and displacement currents—traditionally neglected—may also contribute considerably toward extracellular potential recordings. Here, we first justify the application of the electro‐quasistatic approximation of…

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