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Follicular lymphoma (FL) is a neoplasm of germinal-centre (GC) B cells with varying proportions of centrocytes and centroblasts or large transformed cells and at least a partially follicular growth pattern. In rare cases with an entirely diffuse growth pattern, the neoplastic cells should still show GC B-cell morphology and immunophenotype. ICD-O coding 9690/3 Follicular lymphoma 9698/3 Follicular large B-cell lymphoma 9690/3 Follicular lymphoma with uncommon features ICD-11 coding 2A80.Z Follicular lymphoma, unspecified Related terminology Acceptable: FL grades 1, 2, 3A, and 3B; BCL2-R–negative CD23-positive follicle centre lymphoma (for some cases of FL with dominant diffuse growth pattern only). Subtype(s) Classic FL (cFL); FL with unusual cytological features (uFL); FL with a predominantly diffuse growth pattern (dFL); follicular large B-cell lymphoma (FLBCL) Localization FL predominantly affects lymph nodes. Involvement of the spleen and bone marrow is frequent. Rarely, the Waldey
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