Hyperleukocytosis and leukostasis in hematologic malignancies - UpToDate
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Hyperleukocytosis and leukostasis in hematologic malignancies INTRODUCTION Hyperleukocytosis describes a peripheral white blood cell (WBC) count >100 x 109/L (100,000/microL) in a patient with leukemia. Hyperleukocytosis is most often seen in patients with acute myeloid leukemia (AML), acute lymphoblastic leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia, but always reflects an underlying hematologic malignancy. Leukostasis (ie, symptomatic hyperleukocytosis) is a medical emergency. Leukostasis is a clinical diagnosis in which respiratory distress, central nervous…
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