The MICrONS Project
An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation for discovering the computational bases of cortical circuits.
A cubic millimetre might not sound like much — roughly the size of a grain of sand — but to neuroscientists, it is enormous. One cubic millimetre of a mammalian brain contains tens of thousands of neurons with hundreds of millions of connections, or synapses, between them. For most of the history of neuroscience, tracing the detailed connectivity (or connectomics) and measuring activity of neurons at such a large scale was unthinkable. Instead, neuroscientists worked at more manageable scales — even single pairs of connected cells can provide important information, especially when accrued over
related reading
- Connectome - Wikipediaen.wikipedia.org
- Gap Mapgap-map.org
- A Browsable Petascale Reconstruction of the Human Cortexai.googleblog.com
- On whole-mammalian-brain connectomics – Longitudinal Sciencelongitudinal.blog
- Barcoding Brainspress.asimov.com
- Barcoding Brains - by Alexandra Balwit - Asimov Pressasimov.press
- Mapping the Brain for Alignment | IFPifp.org
- Could a Neuroscientist Understand a Microprocessor? | PLOS Computational Biologyjournals.plos.org
- What's a brain? Explore a real brain in 3Dwhatisabrain.com
- Connectomics beyond electron microscopy | Nature Methodsnature.com
- Convolutional nets for reconstructing neural circuits from brain images acquired by serial section electron microscopyncbi.nlm.nih.gov
- State of Brain Emulation Report 2025 | Research Overviewbrainemulation.mxschons.com