Single-chain variable fragment
A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short peptide linker of ten to about 25 amino acids.
Single-chain variable fragment - Wikipedia Jump to content From Wikipedia, the free encyclopedia Fragment Rotating scFv fragment with highlighted complementarity determining regions (CDRs) The two possible structures of a single-chain variable fragment, with the antigen binding sites including the N-termini on the left and the C-termini on the right. The linker peptides are shown as arrows. A single-chain variable fragment ( scFv ) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (V H ) and light chains (V L ) of immunoglobulins ,
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