All Medications Are Insignificant In The Eyes Of God And Traditional Effect Size Criteria

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All Medications Are Insignificant In The Eyes Of God And Traditional Effect Size Criteria ... Scott Alexander May 31, 2023 299 200 9 Share SSRI antidepressants like Prozac were first developed in the 1980s and 1990s. The first round of studies, sponsored by pharmaceutical companies, showed they worked great! But skeptics found substantial bias in these early trials; several later analyses that corrected for this all found effect sizes (compared to placebo) of only 0.30. Is an effect size of 0.30 good or bad? The usual answer is “bad”. The UK’s National Institute for Clinical Excellence used to

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