Directed differentiation of human induced pluripotent stem cells generates active motor neurons - PMC

The potential for directed differentiation of human induced pluripotent stem (iPS) cells to functional post-mitotic neuronal phenotypes is unknown. Following methods shown to be effective at generating motor neurons from human embryonic stem cells ...

Stem Cells . Author manuscript; available in PMC: 2010 Jul 2. Published in final edited form as: Stem Cells. 2009 Apr;27(4):806–811. doi: 10.1002/stem.31 Directed differentiation of human induced pluripotent stem cells generates active motor neurons S Karumbayaram S Karumbayaram 1 Department of Neurology, David Geffen School of Medicine at UCLA Find articles by S Karumbayaram 1, * , BG Novitch BG Novitch 2 Department of Neurobiology, David Geffen School of Medicine at UCLA 3 Broad Stem Cell Center, UCLA Find articles by BG Novitch 2, 3, ^, * , M Patterson M Patterson 5 Department of Molecular,

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