Mechanisms of Immunosuppression - Holland-Frei Cancer Medicine - NCBI Bookshelf
There is ample evidence that tumor cells produce immunosuppressive factors, and this has been verified to have local as well as systemic effects on immune function. In this section, we will discuss some of the better documented immunosuppressive factors released by tumor cells, their effects on immune function, and some strategies for therapeutic intervention based upon limiting the degree of immunosuppression associated with these molecules.
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