Functionally diverse human insular architecture with memory-related hippocampal interactions | Nature Neuroscience
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Advertisement Nature Neuroscience (2025)Cite this article Direct and simultaneous recordings across the human brain during a memory encoding task involving emotionally valenced words revealed tightly clustered neuronal sites within the insular cortex with distinct roles — some tracked valence, whereas others predicted memory. Only memory-related insular sites, when electrically stimulated, sparked strong hippocampal responses, uncovering a specialized insula–hippocampus axis for successful memory encoding. You have full access to this article via University of California, Berkeley. The hippocampus is essen
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