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Neural prosthesis for hippocampal memory function – Center for Neural Engineering

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Hippocampal memory prosthesis is a Brain Machine Interface device developed for restoring or enhancing memory functions. It is designed to circumvent damaged hippocampal tissue by re-establishing the ensemble coding of spike trains performed by a normal population of hippocampal neurons. The objective is to restore long-term memory function in a stimulus-specific manner using a multi-input, multi-output (MIMO) nonlinear dynamical model. The hippocampus is responsible for the formation of new long-term declarative memories: the formation of mnemonic labels that identify a unifying collection of features and form relations between multiple collections of features. It is the degeneration and malformation of hippocampal neurons that is the underlying cause of the memory disorders associated with stroke, epilepsy, dementia, and Alzheimer’s disease. The hippocampal memory prosthesis is a multi-circuit, biomimetic system that consists of three components: (1) a multi-electrode array for recor

Neural prosthesis for hippocampal memory function Hippocampal memory prosthesis is a Brain Machine Interface device developed for restoring or enhancing memory functions. It is designed to circumvent damaged hippocampal tissue by re-establishing the ensemble coding of spike trains performed by a normal population of hippocampal neurons. The objective is to restore long-term memory function in a stimulus-specific manner using a multi-input, multi-output (MIMO) nonlinear dynamical model. The hippocampus is responsible for the formation of new long-term declarative memories: the formation of mnem

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