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Research | Streichan Lab

streichanlab.physics.ucsb.edu · 1,053 words · saved by 1 readers

The discipline of physics has had striking success in uncovering quantitative laws governing the inanimate world - just think of celestial mechanics. A comparable understanding of the living world, combining quantitative observation and predictive, mathematical models, is still lacking. Our ambition is to uncover the quantitative laws that govern animal development, holding ourselves to the standards of physics. And just as a solid knowledge of electrodynamics and statics is key for any engineer, a quantitative understanding of morphogenesis opens the door to synthetic developmental biology. Members of our lab work on a diverse set of questions in multiple systems, based on shared technology and expertise. Understanding human organ formation is a major scientific challenge. We develop chip-based culture systems to study the self-organization of micropatterned stem cells, which transform into precise three-dimensional cell-fate patterns and organ shapes. Recently, we used this approach

The Streichan lab studies morphogenesis, the process by which developing multicellular organisms obtain their shape. We combine cutting-edge microscopy and quantitative, physics-inspired analysis and modeling to study how cells dynamically coordinate to generate forces and shape tissues. The discipline of physics has had striking success in uncovering quantitative laws governing the inanimate world - just think of celestial mechanics. A comparable understanding of the living world, combining quantitative observation and predictive, mathematical models, is still lacking. Our ambition is to unco

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