Spatial Information | Department of Biology

The capacity to generate a complex organism from the single cell of a fertilized egg is one of the most amazing qualities of multicellular creatures. The processes involved in laying out a basic body plan and defining the structures that will ultimately be formed depend upon a constant flow of information between cells and tissues. The Levin laboratory studies the molecular mechanisms that cells use to communicate with one another in the 4-dimensional dynamical system known as the developing embryo. We also study the flow of information necessary for an injured system to recognize what structures must be rebuilt, and the algorithms that coordinate individual cell activity towards specific patterning outcomes during remodeling and cancer suppression. Through experimental approaches and mathematical modeling, we examine the processes governing large-scale pattern formation and biological information storage during animal embryogenesis and regeneration. Our investigations are directed tow

Spatial Information | Department of Biology Levin Lab Spatial Information Bioelectricity Projects in the Levin Lab Cancer Detection of cancer Neoplastic conversion Tumor normalization Development Crarniofacial patterning Eye induction Left-right asymmetry Regeneration Limb regeneration Head-tail regenerative polarity (planaria) Spinal cord (tail) regeneration The capacity to generate a complex organism from the single cell of a fertilized egg is one of the most amazing qualities of multicellular creatures. The processes involved in laying out a basic body plan and defining the structures that

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