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Anaphylaxis: Emergency treatment - UpToDate

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Anaphylaxis: Emergency treatment Authors:Ronna L Campbell, MD, PhDJohn M Kelso, MD Section Editors:Ron M Walls, MD, FRCPC, FAAEMAdrienne G Randolph, MD, MSc Deputy Editors:Anna M Feldweg, MDMichael Ganetsky, MD Literature review current through: Aug 2026. This topic last updated: Aug 12, 2025. INTRODUCTION Anaphylaxis is a serious, systemic, mast cell-mediated event that can be fatal if not promptly recognized and treated. The goal of therapy is early recognition and treatment with epinephrine to prevent progression to life-threatening respiratory and/or cardiovascular symptoms and…

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