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Receptor theory of drug action | Deranged Physiology

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This chapter answers parts from Section C(i) of the 2023 CICM Primary Syllabus, which asks the exam candidate to "explain the concept of drug action with respect to receptor theory".  Nobody has ever been asked about this in the exams or vivas; nor is it ever likely to emerge as a dominant topic of a future SAQ. The subject matter is sufficiently esoteric and remote from clinical reality that even the CICM examiners are unlikely to view it as a fair discriminator of good trainees from bad. The concept of receptor theory is so well-entrenched and foundational that most trainees of modern medicine cannot conceive of a universe without it. However, it is still possible to throw trainees off with a low-scoring SAQ stem like "What are receptors?" This is exactly what they did in Question 1 from the first paper of 2024, which then went on to ask more relevant questions about agonists and antagonists. Because of this reliance and over-familiarity, any question about receptor theory will come

This chapter answers parts from Section C(i) of the 2023 CICM Primary Syllabus, which asks the exam candidate to "explain the concept of drug action with respect to receptor theory". Nobody has ever been asked about this in the exams or vivas; nor is it ever likely to emerge as a dominant topic of a future SAQ. The subject matter is sufficiently esoteric and remote from clinical reality that even the CICM examiners are unlikely to view it as a fair discriminator of good trainees from bad. The concept of receptor theory is so well-entrenched and foundational that most trainees of modern…

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