Bilirubin metabolism - UpToDate
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Bilirubin metabolism Authors:Namita Roy-Chowdhury, PhD, FAASLDJayanta Roy-Chowdhury, MD, MRCP, AGAF, FAASLD Section Editors:Sanjiv Chopra, MD, MACP, FRCP (London)Elizabeth B Rand, MD Deputy Editor:Claire Meyer, MD Literature review current through: Aug 2026. This topic last updated: Sep 25, 2025. INTRODUCTION Bilirubin is the catabolic product of heme metabolism. Within the physiologic range, bilirubin has cytoprotective and beneficial metabolic effects, but at high levels it is potentially toxic. Fortunately, there are elaborate physiologic mechanisms for its detoxification and…
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