Programmed exosome fusion for energy generation in living cells | Nature Catalysis
The design of artificial organelles for applications in living cells faces several challenges such as cellular uptake, stability and biocompatibility. Now, fusion of exosomes creates beneficial nanoreactors and their use for compartmentalized biocatalytic cascade reactions in cells is demonstrated.
Data availability Data used to generate results in the current study are available from the corresponding author on reasonable request. Source data are provided with this paper. References Agapakis, C. M., Boyle, P. M. & Silver, P. A. Natural strategies for the spatial optimization of metabolism in synthetic biology. Nat. Chem. Biol. 8, 527–535 (2012). Article CAS PubMed Google Scholar Hammes, G. G. & Wu, C.-W. Regulation of enzyme activity. Science 172, 1205–1211 (1971). Article Google Scholar Kondo, S. & Miura, T. Reaction-diffusion model as a framework for understanding…
saved by
related reading
- Interesting Lab Websites | LoganThrasherCollins.comlogancollinsblog.com
- A wavelength-induced frequency filtering method for fluorescent nanosensors in vivonature.com
- For the First Time, a Cell Built From Scratch Grows and Divides | Quanta Magazinequantamagazine.org
- Technologies to measure and modulate protein subcellular localizationnature.com
- Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloidsnature.com
- Application-driven design of non-aqueous electrolyte solutions through quantification of interfacial reactions in lithium metal batteries | Nature Nanotechnologynature.com
- A fingertip-wearable microgrid system for autonomous energy management and metabolic monitoringnature.com
- Biohybrid microswimmer - Wikipediaen.wikipedia.org
- Whole-cell biocatalysts by design | Microbial Cell Factories | Springer Nature Linkmicrobialcellfactories.biomedcentral.com
- Cellular alchemysubstack.com
- Self-driving laboratories to autonomously navigate the protein fitness landscapenature.com
- 3D bioprinting of cells, tissues and organs | Scientific Reportsnature.com