Cancer risk across mammals | Nature
An analysis of cancer mortality data for zoo mammals highlights marked differences across mammalian orders and an influence of diet, and shows that mortality risk is largely independent of body mass and life expectancy across species.
Main Complex multicellular organisms are built of millions to quadrillions of cells, ultimately all being derived from a single cell, the zygote. During the course of the organisms’ lifetime and owing to various mutational processes, cell lineages tend to accumulate mutations7,8. While the majority of mutations are harmless, some enable cells to escape cell cycle control, to grow and proliferate uncontrollably, resulting in cancer9,10. Cancer is a multistage process, where a set of mutations is required for both initiation and malignant progression. Given that every cell division carries a…
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