Evaluation and diagnosis of multiple sclerosis in adults - UpToDate

{{configCtrl2.info.metaDescription}}

Evaluation and diagnosis of multiple sclerosis in adults INTRODUCTION Multiple sclerosis (MS) is the most common immune-mediated inflammatory demyelinating disease of the central nervous system. MS is characterized pathologically by multifocal areas of demyelination, accompanied by oligodendrocyte loss and astroglial scarring. Axonal injury is also a prominent pathologic feature, especially in the later stages. Certain clinical features are typical of MS, but the disease has a highly variable pace and many atypical forms. The diagnosis and differential diagnosis of MS are reviewed here.…

related reading

• Clinical presentation, course, and prognosis of multiple sclerosis in adultsuptodate.com
• Neuromyelitis optica spectrum disorder (NMOSD): Clinical features and diagnosisuptodate.com
• ALS - Wikipediaen.wikipedia.org
• Staging of brain pathology related to sporadic Parkinson's disease - PubMedpubmed.ncbi.nlm.nih.gov
• Spinal column injuries in adults: Types, classification, and mechanismsuptodate.com
• MRI Basicscase.edu
• Clinical manifestations of myasthenia gravisuptodate.com
• Evaluation of the adult with acute weakness in the emergency departmentuptodate.com
• Neuromyelitis optica spectrum disorders - PMCncbi.nlm.nih.gov
• Association of anti-NXP2 antibody with clinical characteristics and outcomes in adult dermatomyositis: results from clinical applications based on a myositis-specific antibody - PubMedpubmed.ncbi.nlm.nih.gov
• The Glymphatic System – A Beginner's Guidencbi.nlm.nih.gov
• Clinical Diagnostic Accuracy of Parkinson's Disease: Where Do We Stand? - PubMedpubmed.ncbi.nlm.nih.gov