Neuromyelitis optica spectrum disorders (NMOSD): Clinical features and diagnosis - UpToDate

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Neuromyelitis optica spectrum disorder (NMOSD): Clinical features and diagnosis INTRODUCTION Neuromyelitis optica spectrum disorder (NMOSD; previously known as Devic disease or neuromyelitis optica [NMO]) is an inflammatory disorder of the central nervous system characterized by severe, immune-mediated demyelination and axonal damage predominantly targeting optic nerves and the spinal cord. The epidemiology, pathogenesis, clinical manifestations, and diagnosis of NMOSD will be reviewed here. Treatment and prognosis are reviewed separately. (See "Neuromyelitis optica spectrum disorder…

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