Chapter 6: Registration and Normalization — Andy's Brain Book 1.0 documentation
Although most people’s brains are similar - everyone has a cingulate gyrus and a corpus callosum, for instance - there are also differences in brain size and shape. As a consequence, if we want to do a group analysis we need to ensure that each voxel for each subject corresponds to the same part of the brain. If we are measuring a voxel in the visual cortex, for example, we would want to make sure that every subject’s visual cortex is in alignment with each other.
Overview Although most people’s brains are similar - everyone has a cingulate gyrus and a corpus callosum, for instance - there are also differences in brain size and shape. As a consequence, if we want to do a group analysis we need to ensure that each voxel for each subject corresponds to the same part of the brain. If we are measuring a voxel in the visual cortex, for example, we would want to make sure that every subject’s visual cortex is in alignment with each other. This is done by Registering and Normalizing the images. Just as you would fold clothes to fit them inside of a…
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