The Case Time Series Design - PMC

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. Author manuscript; available in PMC: 2022 May 1. Abstract Modern data linkage and technologies provide a way to reconstruct detailed longitudinal profiles of health outcomes and predictors at the individual or small-area level. While these rich data resources offer the possibility to address epidemiologic questions that could not be feasibly examined using traditional studies, they require innovative analytical approaches. Here we present a new study design, called case time series, for epidemiologic investigations of transient health risks associated with time-varying exposures. This…

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