On whole-mammalian-brain connectomics

In response to David Markowitz’s questions on Twitter: 1. What are current obstacles to generating a connectomic map of a whole mammalian brain at nanometer scale? 2. What impt questions coul…

adamhmarblestone Uncategorized January 1, 2019 January 20, 2019 15 Minutes In response to David Markowitz’s questions on Twitter: https://twitter.com/neurowitz/status/1080131620361912320 1. What are current obstacles to generating a connectomic map of a whole mammalian brain at nanometer scale? 2. What impt questions could we answer with n=1? n=2? 3. What new analysis capabilities would be needed to make sense of whole brain data? Responses : David himself knows much or all of the below, as he supported a lot of the relevant work through the IARPA MICRONS program (thank you), and I have

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