Evolutionary Scale · ESM Cambrian: Revealing the mysteries of proteins with unsupervised learning
Today we’re introducing ESM Cambrian, a next generation language model trained on protein sequences at the scale of life on Earth. ESM C models define a new state of the art for protein representation learning. AI is beginning to unlock an era of digital biology where we can use computation to go beyond the limits of experiments in the physical world. The universe of protein function is so vast and complex that we lack the ability to fully characterize it experimentally, and for many applications, we need to engineer functions that go beyond those in nature. The physical limitations of performing experiments in the real world mean that unsupervised learning—algorithms that can learn from patterns in unlabeled data—is critical to unlocking the promise of digital biology. Discovering scalable techniques that can learn directly from protein sequences can illuminate biology at a level not yet possible with experimental characterization. ESM Cambrian is a parallel model family to our fl
Evolutionary Scale · ESM Cambrian: Revealing the mysteries of proteins with unsupervised learning By using this website, you agree to the storing of cookies on your device to analyze site usage. View our Privacy Policy for more information. Deny Accept Start working with ESM Use ESM3 December 4, 2024 // Announcement ESM Cambrian: Revealing the mysteries of proteins with unsupervised learning Start with ESM C on Github Provision on SageMaker Today we’re introducing ESM Cambrian, a next generation language model trained on protein sequences at the scale of life on Earth. ESM C models define a ne
related reading
- Evolutionary Scale · ESM3: Simulating 500 million years of evolution with a language modelevolutionaryscale.ai
- GitHub - Biohub/esmgithub.com
- Protein World Model | Biohubbiohub.ai
- Language models of protein sequences at the scale of evolution enable accurate structure predictionbiorxiv.org
- Highly accurate protein structure prediction with AlphaFoldnature.com
- Have We Hit the Scaling Wall for Protein Language Models?pascalnotin.substack.com
- Pathways Language Model (PaLM): Scaling to 540 Billion Parameters for Breakthrouai.googleblog.com
- Towards the explainability of protein language modelsnature.com
- Evo 2 Can Design Entire Genomesasimov.press
- Intuition on AI Scale for Biologistsbiotechbio.substack.com
- Anthrogenanthrogen.com
- An Introduction to Exemplar Partitioning for Mechanistic Interpretability — LessWronglesswrong.com