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From molecular to modular cell biology | Nature

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Cellular functions, such as signal transmission, are carried out by ‘modules’ made up of many species of interacting molecules. Understanding how modules work has depended on combining phenomenological analysis with molecular studies. General principles that govern the structure and behaviour of modules may be discovered with help from synthetic sciences such as engineering and computer science, from stronger interactions between experiment and theory in cell biology, and from an appreciation of evolutionary constraints.

References Stock, J. B. & Surette, M. G. in Escherichia coli and Salmonella: Cellular and Molecular Biology (eds Neidhardt, F. C. & Curtiss, R.) 1103–1129 (ASM Press, Washington, DC, 1996). Google Scholar Herskowitz, I. Cell 80, 187–197 ( 1995). Article CAS Google Scholar Posas, F., Takekawa, M. & Saito, H. Curr. Opin. Microbiol. 1, 175 –182 (1998). Article CAS Google Scholar Hsu, H. et al. Biophys. J. 65, 1196–1206 (1993). Article ADS CAS Google Scholar Waxman, D. & Peck, J. R. Science 279, 1210–1213 (1998). Article ADS CAS Google Scholar Konopka, J. B., Jenness, D. D. &…

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