Depression, opioids and the HPA

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Depression, opioids and the HPA The effect of naloxone on adrenocorticotropin and cortisol release: evidence for a reduced response in depression by Burnett FE, Scott LV, Weaver MG, Medbak SH, Dinan TG Department of Psychological Medicine, The Medical Colleges of St. Bartholomew's and the Royal London Hospitals, West Smithfield, UK. J Affect Disord 1999 Jun; 53(3):263-8 ABSTRACT B ACKGROUND: Endogenous opioid peptides inhibit the hypothalamic-pituitary-adrenal (HPA) axis by influencing the release of hypothalamic corticotropin releasing factors. This study examines whether increased activity o

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